There’s no denying the funky presence of Karl Denson’s Tiny Universe – not even The Rolling Stones could deny the awesome talent that Denson brings to the table. The band captures a unique soul/funk groove that just won’t quit, but there’s always room for friends to stop by and join in the party. That’s exactly what happened earlier this year, when guitarist Jimmy Herring made his way to a KDTU performance at Tipitina’s during Jazz Fest season.Watch what happens when these entities get together, below.Fortunately, Herring and KDTU have announced a four-date excursion this fall, hitting venues from November 30th through December 3rd.? The shows will stretch through the Southeast, hitting spots in Georgia and North Carolina. The full tour schedule can be seen below!Karl Denson’s Tiny Universe with Jimmy Herring11/30 Athens, GA at Georgia Theatre12/01 Asheville, NC at New Mountain Asheville12/02 Charlotte, NC at Neighborhood Theatre12/03 Atlanta, GA at Terminal West
Nima Saeidi, an assistant professor of surgery at Harvard Medical School and Massachusetts General Hospital and a member of the Center for Engineering in Medicine, had started down one career path when a lecture on Roux-en-Y gastric bypass surgery redirected him.The MGH lecture outlined not just the procedure’s striking effectiveness for weight loss — averaging 40 percent — but also its promise against diabetes, high blood pressure, cholesterol, and fatty-food cravings. Saeidi, an assistant in bioengineering at MGH, halted his work in tissue engineering and began to study gastric bypass.“To me, it’s really a mystery,” said Saeidi, “and it seems to be like a miracle.”The idea of a compound that mimics the positives of?Roux-en-Y is particularly enticing amid twin national epidemics of obesity and diabetes. A therapy that conferred the surgery’s benefits while avoiding its less healthy side effects — brittle bones, vitamin deficiency, anemia, and increased rates of alcoholism — would likely add significantly to the 45,000 morbidly obese patients the procedure helps annually.The problem is scientists still don’t know how it works.In?Roux-en-Y, physicians make a small pouch out of the upper portion of the stomach and then cut and reattach the small intestine to the pouch, bypassing the entire lower stomach and the first few feet of the small intestine. This transformation of the stomach into a pouch makes patients feel full quickly, while food’s rapid passage into the intestine alters digestion and absorption of calories — as well as of minerals and vitamins, the cause of some of the surgery’s negative side effects.The surgery was developed decades ago as a treatment for stomach ulcers, and was first used as a correction for morbid obesity by University of Iowa physicians in 1967. Follow-up research uncovered dramatic benefits independent of weight loss.For example, though Type 2 diabetes risk is tied to obesity, post-Roux-en-Y resolution of the disease — more than 80 percent of patients are cured — is not solely a weight-loss phenomenon.“We see effects happening within two to three days,” Saeidi said. “Patients get surgery and they’re completely diabetic, they need insulin or metformin medication. And many of them leave the hospital without any medication. It is just puzzling how this is happening and what is causing it.”There were 64?Roux-en-Y procedures at MGH last year. The surgery has been shown to affect insulin sensitivity and production of the hunger hormones ghrelin and leptin. It also alters the composition of a patient’s microbiome, the intestinal bacteria that scientists are beginning to understand play a major role in health. Harvard researchers are targeting obesity and its cousin, diabetes Alcohol abuse after weight loss surgery? Study suggests possible alternative to gastric bypass surgery Researchers gather at Radcliffe to investigate gut-brain communication Related Obesity? Diabetes? We’ve been set up Major weight loss tied to microbes Initially, Saeidi said, researchers searched for a single enzyme or hormone responsible for the changes. But consensus has gradually turned away from a “silver bullet” for what appears to be a fundamental shift in metabolism.“The previous work was on single tissue, but it became very apparent it’s not just a story about one single organ or one single tissue,” Saeidi said. “It is the crosstalk and interaction between different organs that really drives the systemic effects.”That crosstalk is likely to involve a network of cascading changes in fat, muscle, the liver, and intestines. To better probe that complexity, Saeidi and colleagues have turned to new rodent models, spectroscopic instruments, and novel informatics techniques that shift inquiry from a traditional hypothesis-based, step-by-step exploration to one that seeks to reverse-engineer the problem, by searching broadly for postoperative chemical changes in the body and then working to understand them.“This is an agnostic, hypothesis-generation tool,” said Gautham Sridharan, a recent fellow in Saeidi’s lab and first author of a paper on their work published in the journal Technology. “Post RYGB, we see all these changes … in metabolism. It gives us some clue that maybe we should further investigate that pathway.”In a Roux-en-Y rodent model, Saeidi’s team identified more than 1,300 liver proteins and searched for changes in their concentration 30 days later. Eighty-two had changed and two of them, Thrsp and Acot13, appeared to be potential drug targets. Though that may seem a promising start, Sridharan noted that the study examined only one organ and at just one point in what appears to be a dynamic post-surgery process involving several organs.Future research, Saeidi said, will examine compounds whose altered concentrations in one organ move through the blood to where they can affect others.“Ideally, we want to have a sense of the dynamics of the changes that occur in different organs and how different organs interact with each other,” Saeidi said.
View Comments The diva is back in the building! Before she flies off to space, original Phantom of the Opera headliner Sarah Brightman will return to the Broadway production as hot-headed opera star Carlotta, opposite Norm Lewis as The Phantom and Sierra Boggess as Christine Daae.The international recording star will start performances in the role in mid-May at the Majestic Theatre…. In our dreams!?HAPPY APRIL FOOLS’ DAY! Star Files Sierra Boggess
By Diálogo February 07, 2020 In early January, Twitter suspended dozens of accounts linked to the Nicolás Maduro regime citing “platform manipulations.” Maduro’s presidential office, the Bolivarian Armed Forces’ Strategic Operational Command, the Central Bank of Venezuela, including state oil company PDVSA, and other government agencies temporarily lost access to their accounts.In 2019, both Twitter and Facebook took down thousands of accounts linked to disinformation campaigns in Iran, Russia, and Venezuela. In Venezuela, Twitter removed about 2,000 accounts that were considered by the company to be engaging in “state-backed influence campaigns targeting domestic audiences.”According to a 2019 report on online propaganda by Oxford University, seven countries were singled out for using social media to control information and to influence audiences, including China, Iran, Russia, and Venezuela. The report indicates that the Venezuelan regime not only relies on bots (automated software applications), but also on a large budget and large number of people tasked with manipulating public opinion online. The report estimates that “multiple brigades of 500 people” with “evidence of formal training” carry out computational propaganda for the regime.According to Venezuelan journalist Adrian González, who operates Cazadores de Fake News (Fake News Hunters), one of six Venezuelan fact-checking sites that verify materials circulating on online platforms and fight disinformation, many of Maduro’s brigades operate from two call centers in Caracas and receive orders directly from the Venezuelan Ministry of Communication and Information.“Some of those [accounts] are easy to catch, with bot behavior,” González said. “They retweet between 100 to 400 times a day, but you can see they are human operators […]. I’ve denounced these accounts thousands of times.”González said the brigades are lured with easy money earned by simply engaging in disinformation campaigns to suppress the opposition and to reinforce the regime’s message.“With prizes, that’s how they get people to tweet,” González said. “They say position this trend, get $10. With a little bit of money you can incentivize a whole lot of people and there are some who spend their entire time doing just that.”A document from the Venezuelan Ministry of the Interior and Justice, “Formation Project for the Bolivarian Revolution Army of Trolls,” leaked in 2017 to the Press and Society Institute of Venezuela detailed the regime’s online propaganda plan of action. According to the document, the “Army” consists of squadrons (1 person), pelotons (10 people), companies (50 people), battalions (100 people), and brigades (500 people), who are responsible for operating from 23 to 11,500 accounts in the most popular social media sites. The trolls are categorized as pro-government, (false) opposition (pro-Maduro trolls whose online task is to infiltrate the opposition and interfere in their conversation), neutral, distraction, and fake news. Their role is to monitor online content and spread false information.According to González, the trolls owe their social media savvy to training they received as part of the Maduro regime’s “Robinson Digital Mission“ a 2016 initiative under the Ministry of Education. State-owned media described the mission as a “new digital capability sought by the State to counter the communications warfare the national and international right is waging.”“I am creating the Robinson Digital Mission […] to defend the people of Venezuela’s right to truth, independence, and peace,” Maduro said as he approved the mission’s creation.In her late 2018 study, “Venezuelan Government Strategies for Information War on Twitter,” Iria Puyosa, a Venezuelan researcher in political communication and a visiting professor at Brown University’s Center for Latin American and Caribbean Studies, identified three strategies the Maduro regime uses on Twitter to manipulate public opinion. Puyosa’s research indicates that the regime coordinates official accounts and those of its Army of trolls to ensure the reach of daily trending topics, to promote distracting hashtags with misleading or false information, and to hijack the hashtags of the opposition to alter their message and meddle in their conversations.“The combined deployment of the three strategies constitutes a systemic violation of Venezuelan internet users’ right to participate in public affairs,” Puyosa said in her report. “Furthermore, these strategies contributed to the violation of expression and association, access to information, and participation in public affairs debates, which are fundamental to a free, open, and human rights-oriented internet.”
The Federal Reserve 6SHARESShareShareSharePrintMailGooglePinterestDiggRedditStumbleuponDeliciousBufferTumblr The Federal Reserve Board put its stamp of approval on same-day ACH Wednesday, but not without objections from members of the credit union industry.A review of letters sent to the Fed during the public comment period highlights two of the most controversial parts of the new rules: The requirement that receiving depository institutions accept same-day ACH transactions, and the cost of those transactions. continue reading ?
News DR Congo colonel Kibibi Mutware jailed for mass rape by: – February 21, 2011 Tweet 53 Views ? no discussions BBC News Share Share Share Sharing is caring! It is unusual for rape victims to be willing to testify in such large numbersA military court in eastern Democratic Republic of Congo investigating a case of mass rape has sentenced Lt Col Kibibi Mutware to 20 years in jail.He was found guilty of crimes against humanity for sending his troops to rape, beat up and loot from the population of Fizi on New Year’s Day.Forty-nine women came to testify in the court in in Baraka.The BBC’s Thomas Hubert says it is the first conviction of a commanding officer for rape in eastern DR Congo.Humanitarian agencies regularly cite government troops as the largest single group of perpetrators of widespread sexual violence in the Kivu region, says our reporter, who is in the town of Baraka, not far from Fizi.Sitting in a mobile court in Baraka, the military judges also sentenced three officers serving under Lt Col Kibibi to 20 years and five soldiers to between 10 and 15 years.Unusual testimoniesLt Col Kibibi Mutware is one of many former rebels who joined the army as part of peace agreements in 2009.More than 60 women were raped on 1 January in Fizi.Our reporter says it is unusual for such large numbers of victims in eastern DR Congo to be willing to testify against their rapists.Ahead of the verdict, many of them gathered at the rape victims’ centre in Fizi.“I was fleeing the violence but unfortunately I met four soldiers, ” a 29-year-old mother of five told the BBC about the events on New Year’s day.?“They began to tear the pants I was wearing. They took my child from my arms and left him on the ground. Then they had sex with me.”In August 2010, rebel forces were accused of raping hundreds of women, girls, men and boys around the town of Luvungi.The UN recorded some 11,000 rapes in 2010 – the true figure is believed to be much higher.Our reporter says since January there have been other reports of sexual violence in an area where the Rwandan FDLR rebels are still active, 40km (about 25 miles) from Fizi.Medical charity Medecins Sans Frontieres says it is planning to deploy a mobile clinic to the area on Monday after receiving credible reports of 30 new rapes last week.It says it has treated more than 70 victims of rapes in two similar incidents in the area between 19 January and 4 February.
During that meeting, the provincial governments of Iloilo, Antique, Aklan, and Capiz agreed to do it. However, it did not push through for still unclear reasons. According to this city’s Mayor Jerry Tre?as, he and governors Arthur Defensor Jr. (Iloilo), Rhodora Cadiao (Antique), Florencio Miraflores (Aklan), Esteban Evan Contreras (Capiz), and Samuel Gumarin (Guimaras) also agreed that airports and seaports would remain closed except for the transport of returning stranded residents of the region, and delivery of essential goods. * repatriates – 35 (Aklan, two; Antique, four; Guimaras, three; Iloilo province, four; Negros Occidental, seven; Bacolod City, four; Iloilo City, 11) * Capiz – six Public gatherings such as movie screenings, concerts, sporting events and other entertainment activities will be allowed, but participants may fill no more than half of the capacity of the venue. Negros Occidental’s Gov. Jose Eugenio Lacson and Bacolod City’s Mayor Evelio Leonardia also attended the virtual meeting of Tre?as and the governors but did not right away commit to open their borders, citing their uncertainty as to when the trips of fast crafts between Negros Occidental / Bacolod City and Panay Island would resume. All persons will be allowed outside their houses, although minimum public health standards will still have to be complied with. ILOILO City – For the unhampered flow of people, vehicles and goods beginning June 1, this city, the provinces of Iloilo, Antique, Aklan, Capiz, and Guimaras would be opening their borders. There would be no more border restrictions and quarantine passes would no longer be required. Here’s the breakdown of the 113 cases: A modified general community quarantine is the transition phase between general? community quarantine and the “new normal” when restrictions are further relaxed and become less necessary such as limiting people’s movement and public transportation, the operation of industries and the presence of uniformed personnel to enforce community quarantine. They also agreed to continue requiring returning overseas workers and returning stranded local residents to undergo 14 days of quarantine and RT-PCR (reverse transcription polymerase chain reaction) test for coronavirus disease 2019 (COVID-19). “Para hindi magkagulo…kasi nangyayari ngayon, iba’t-iba ang policies” on community quarantine-related border restrictions in response to the COVID-19 pandemic, he lamented. “Kita willing magbaton sa ila, sila lang ang daw indi pa. Mahulat kita kon san-o sila ready na,” said Tre?as. Early this week, Assistant Secretary Jonji Gonzales of the Office of the Presidential Assistant for the Visayas pushed for a “one Panay policy” on quarantine covering the islands of Panay and Guimaras. According to Cadiao, the provincial governors and Tre?as aimed to have uniform quarantine policies by June 1 when the region transitions to a modified general community quarantine. The governors agreed that harmonizing the rules would ease the inconvenience that the restrictions would bring on people, especially those crossing provincial boarders due to work and business, among others./PN Antique’s Governor Cadiao said her fellow governors also agreed to maintain border checkpoints but not to block travel; the police would just be tasked to ensure that travelers observe minimum health safety protocols such as the wearing of facemasks and observing social distancing in vehicles. Gonzales’ suggestion for a unified quarantine policy is not new. It was Mayor Tre?as who pushed for the harmonization of border restrictions during the March 16 meeting of the Regional Disaster Risk Reduction and Management Council at the National Economic and Development Authority (NEDA) Region 6 office here. * Guimaras – zero * Antique – 14 * Aklan – six * Bacolod City – 10 Thus, according to the Department of Health, the region’s active COVID-19 cases stood at only 22. As of yesterday, May 29, the confirmed COVID-19 cases in Western Visayas stood at 113 with 81 patients having recovered and 10 mortalities. Western Visayas would be under a modified general community quarantine by June 1. * Negros Occidental – three * Iloilo province – 20 * Iloilo City – 19 As originally planned, the unified rules and regulations for the border restrictions would be released before April 1. A unified quarantine policy would make it easier for local authorities to manage their borders and the return of stranded individuals such as overseas workers, said Gonzales. The same rule will apply to religious gatherings, community assemblies and non-essential work gatherings.
The Cross Country Semi-States took place at Shelbyvile. The Brebeuf Jesuit Lady Braves won The Girls Semi-States team title and The Carmel Greyhounds won The Boys crown.Congrats to Brenna Hanna of The Greensburg Lady Pirates on qualifying to The State Finals at Terre Haute on Saturday, October 28th.Greensburg finished 9th, East Central 14th, and Franklin County 21st to finish up the season.? The area Boys runners wrapped up their season at The Semi-States.2017 Girls CC Semi-States @ Shelbyville2017 Boys CC Semi States @ Shelbyville
Photo: DCSODearborn County, In. —?The Dearborn County Sheriff’s Department needs your help to find a missing 17-year-old girl last seen Monday afternoon.A report from the sheriff’s department says Whitley Sierra McCabe was last seen around 2:10 p.m. walking in a filed in the 7600 block of York Ridge Road. She is described as 5-feet 4-inches tall, 150 pounds, brown hair and blue eyes. She was wearing a pink and blue hooded sweatshirt, black shorts and work boots.Any information about McCabe can be left by calling 812-537-3431.